Below steps can be used to do many other similar tasks, relate to oem Agents.
- Click Setup > Manage Cloud Control > Agents
 - Select the number in column "Monitored Targets" for the 1st node
 - There you can select the Cluster and Cluster Database
 - Once selected, click Cluster (on top left)
 - Click Target Setup > Remove Target
 - Click Yes to confirm
 - (Do similar with other nodes)